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MENIN Loss as a Tissue-Specific Driver of Tumorigenesis
The MEN1 gene encodes MENIN, a tumor suppressor that plays a role in multiple cellular processes. Germline and somatic mutations in MEN1 have been identified in hereditary and sporadic tumors of neuroendocrine origins suggesting context-specific functions. In this review, we focus on the development...
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| Publié dans: | Mol Cell Endocrinol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064664/ https://ncbi.nlm.nih.gov/pubmed/28965973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.09.032 |
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