Regulation of TGFβ Signalling by TRPV4 in Chondrocytes

The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular functions, how their signals are integrated is unknown. Here we show that pharmacological a...

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Woods, Steven, Humphreys, Paul A., Bates, Nicola, Richardson, Sophie Alice, Kuba, Shweta Yogesh, Brooks, Imogen R., Cain, Stuart A., Kimber, Susan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064313/
https://ncbi.nlm.nih.gov/pubmed/33805168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040726
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