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Hypoxia-induced miR-27 and miR-195 regulate ATP consumption, viability, and metabolism of rat cardiomyocytes by targeting PPARγ and FASN expression

This study examined whether hypoxia-induced microRNA (miRNA) upregulation was related to the inhibition of chondriosome aliphatic acid oxidation in myocardial cells under anoxia. We showed that anoxia induced high expression of hypoxia-inducible factor-1-alpha, muscle carnitine palmitoyltransferase...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Lin, Jintuan, Maimaitiyiming, Atikaimu, Chen, Shaoxi, Xiao, Min, Xian, Zhanchao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064185/
https://ncbi.nlm.nih.gov/pubmed/33819184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202778
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