A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice

Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, and synapse formation. However, how altered electrical activity early in life affects neuronal function and behavior...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuron
Prif Awduron: Bitzenhofer, Sebastian H., Pöpplau, Jastyn A., Chini, Mattia, Marquardt, Annette, Hanganu-Opatz, Ileana L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063718/
https://ncbi.nlm.nih.gov/pubmed/33675685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.02.011
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