Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice

INTRODUCTION: Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer’s disease (AD). Besides direct neuronal injury and neuroinflammation, vascular impairment is also a hallmark event of the pathological cascade after TBI. However, the vascular connecti...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Wu, Yingxi, Wu, Haijian, Zeng, Jianxiong, Pluimer, Brock, Dong, Shirley, Xie, Xiaochun, Guo, Xinying, Ge, Tenghuan, Liang, Xinyan, Feng, Sudi, Yan, Youzhen, Chen, Jian-Fu, Sta Maria, Naomi, Ma, Qingyi, Gomez-Pinilla, Fernando, Zhao, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063402/
https://ncbi.nlm.nih.gov/pubmed/33892818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01178-7
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