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PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma
Oral tongue squamous cell carcinoma (OTSCC) is a highly malignant type of tumor. The 5-year survival rate of patients with advanced tongue squamous cell carcinoma is only ~50%. Pyruvate kinase M2 (PKM2) is the key rate-limiting enzyme of glycolysis, maintaining the Warburg effect in tumor cells. The...
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| Publicado en: | Oncol Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063272/ https://ncbi.nlm.nih.gov/pubmed/33907571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12722 |
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