Dapagliflozin Added to Verinurad Plus Febuxostat Further Reduces Serum Uric Acid in Hyperuricemia: The QUARTZ Study

CONTEXT: Combining a sodium-glucose cotransporter 2 inhibitor with a xanthine oxidase inhibitor (XOI) and a urate transporter 1 (URAT1) inhibitor may enhance serum uric acid (sUA) lowering. However, concerns exist regarding high urinary UA (uUA) excretion rates and subsequent crystallization in rena...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Stack, Austin G, Han, David, Goldwater, Ronald, Johansson, Susanne, Dronamraju, Nalina, Oscarsson, Jan, Johnsson, Eva, Parkinson, Joanna, Erlandsson, Fredrik
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Clinical Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063233/
https://ncbi.nlm.nih.gov/pubmed/33075806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa748
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