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Alpha-1 Acid Glycoprotein as a Biomarker for Subclinical Illness and Altered Drug Binding in Rats

Alpha-1 acid glycoprotein (AGP) is a significant drug binding acute phase protein that is present in rats. AGP levels are known to increase during tissue injury, cancer and infection. Accordingly, when determining effective drug ranges and toxicity limits, consideration of drug binding to AGP is ess...

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Detalhes bibliográficos
Publicado no:Comp Med
Main Authors: Boyle, Catherine A, Coatney, Robert W, Wickham, Alexandra, Mukherjee, Suman K, Meunier, LaVonne D
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063197/
https://ncbi.nlm.nih.gov/pubmed/33789781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-CM-20-000088
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