Mesenchymal derived exosomes enhance recovery of motor function in a monkey model of cortical injury

BACKGROUND: Exosomes from mesenchymal stromal cells (MSCs) are endosome-derived vesicles that have been shown to enhance functional recovery in rodent models of stroke. OBJECTIVE: Building on these findings, we tested exosomes as a treatment in monkeys with cortical injury. METHODS: After being trai...

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Pubblicato in:Restor Neurol Neurosci
Autori principali: Moore, T.L., Bowley, B.G.E., Pessina, M.A., Calderazzo, S.M., Medalla, M., Go, V., Zhang, Z.G., Chopp, M., Finklestein, S., Harbaugh, A.G., Rosene, D.L., Buller, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062985/
https://ncbi.nlm.nih.gov/pubmed/31282441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/RNN-190910
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