Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2

The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested against SARS-CoV-2. Remdesivir is the drug of choice for Ebola virus disease an...

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Bibliografiska uppgifter
I publikationen:Front Mol Biosci
Huvudupphovsmän: Kumar D, Thirumal, Shaikh, Nishaat, Kumar S, Udhaya, Doss C, George Priya, Zayed, Hatem
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Molecular Biosciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062963/
https://ncbi.nlm.nih.gov/pubmed/33898520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.645216
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