Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma

Intratumoral drug delivery is a promising approach for the treatment of glioblastoma multiforme (GBM). However, drug washout remains a major challenge in GBM therapy. Our strategy, aimed at reducing drug clearance and enhancing site-specific residence time, involves the local administration of a mul...

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Vydáno v:Nanoscale
Hlavní autoři: Brachi, Giulia, Ruiz-Ramírez, Javier, Dogra, Prashant, Wang, Zhihui, Cristini, Vittorio, Ciardelli, Gianluca, Rostomily, Robert C., Ferrari, Mauro, Mikheev, Andrei M., Blanco, Elvin, Mattu, Clara
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2020
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062960/
https://ncbi.nlm.nih.gov/pubmed/33237080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0nr05053a
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