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Age-Related Memory Impairment and Sex-Specific Alterations in Phosphorylation of the Rpt6 Proteasome Subunit and Polyubiquitination in the Basolateral Amygdala and Medial Prefrontal Cortex

Aging is marked by an accumulation of damaged and modified brain proteins, and the ubiquitin-proteasome system (UPS) is important for cellular protein degradation. Recent work has established a critical role for the UPS in memory and synaptic plasticity, but the role of the UPS in age-related cognit...

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Bibliografski detalji
Izdano u:Front Aging Neurosci
Glavni autori: Dulka, Brooke N., Trask, Sydney, Helmstetter, Fred J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062735/
https://ncbi.nlm.nih.gov/pubmed/33897408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.656944
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