TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer

The treatment and prognosis of advanced colorectal cancer (CRC) remain a challenging clinical research focus. Here, we describe a new CRC tumor suppressor and potential therapeutic target: thymocyte selection associated high mobility group box (TOX) protein. The expression of TOX was lower in CRC th...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Yang, Mengdi, Huang, Qianru, Li, Changcan, Jiang, Zhiyuan, Sun, Jing, Wang, Zhiyu, Liang, Rui, Li, Dan, Li, Bin, Zhao, Hui
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062716/
https://ncbi.nlm.nih.gov/pubmed/33897695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647540
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