Glutathione-related genetic polymorphisms are associated with mercury retention and nephrotoxicity in gold-mining settings of a Colombian population

Mercury (Hg) vapor can produce kidney injury, where the proximal tubule region of the nephron is the main target of the Hg-induced oxidative stress. Hg is eliminated from the body as a glutathione conjugate. Thus, single nucleotide polymorphisms (SNPs) in glutathione-related genes might modulate the...

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Published in:Sci Rep
Main Authors: Medina Pérez, Olga Marcela, Flórez-Vargas, Oscar, Rincón Cruz, Giovanna, Rondón González, Fernando, Rocha Muñoz, Linda, Sánchez Rodríguez, Luz Helena
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062595/
https://ncbi.nlm.nih.gov/pubmed/33888803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88137-3
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