ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance

Cyclic dinucleotide (CDN) agonists of the STimulator of InterferoN Genes (STING) pathway have shown immune activation and tumor clearance in pre-clinical models. However, CDNs administered intratumorally also promote STING activation leading to direct cytotoxicity of many cell types in the tumor mic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Jang, Su Chul, Economides, Kyriakos D., Moniz, Raymond J., Sia, Chang Ling, Lewis, Nuruddeen, McCoy, Christine, Zi, Tong, Zhang, Kelvin, Harrison, Rane A., Lim, Joanne, Dey, Joyoti, Grenley, Marc, Kirwin, Katherine, Ross, Nikki L., Bourdeau, Raymond, Villiger-Oberbek, Agata, Estes, Scott, Xu, Ke, Sanchez-Salazar, Jorge, Dooley, Kevin, Dahlberg, William K., Williams, Douglas E., Sathyanarayanan, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062530/
https://ncbi.nlm.nih.gov/pubmed/33888863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02004-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados