Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus

Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, snake venom proteins have demonstrated antiviral activity aga...

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izdano v:Sci Rep
Main Authors: Santos, Igor Andrade, Shimizu, Jacqueline Farinha, de Oliveira, Débora Moraes, Martins, Daniel Oliveira Silva, Cardoso-Sousa, Léia, Cintra, Adélia Cristina Oliveira, Aquino, Victor Hugo, Sampaio, Suely Vilela, Nicolau-Junior, Nilson, Sabino-Silva, Robinson, Merits, Andres, Harris, Mark, Jardim, Ana Carolina Gomes
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062466/
https://ncbi.nlm.nih.gov/pubmed/33888774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88039-4
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