Prognostic and predictive impact of stroma cells defined by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial

PURPOSE: Predictive biomarkers are needed to aid the individualization of radiotherapy (RT) in breast cancer. Cancer-associated fibroblasts have been implicated in tumor radioresistance and can be identified by platelet-derived growth factor receptor-beta (PDGFRb). This study aims to analyze how PDG...

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Detalles Bibliográficos
Publicado en:Breast Cancer Res Treat
Autores principales: Strell, Carina, Stenmark Tullberg, Axel, Jetne Edelmann, Reidunn, Akslen, Lars Andreas, Malmström, Per, Fernö, Mårten, Holmberg, Erik, Östman, Arne, Karlsson, Per
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2021
Materias:
Preclinical Study
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062362/
https://ncbi.nlm.nih.gov/pubmed/33661437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-021-06136-4
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