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Whole-organism eQTL mapping at cellular resolution with single-cell sequencing

Genetic regulation of gene expression underlies variation in disease risk and other complex traits. The effect of expression quantitative trait loci (eQTLs) varies across cell types; however, the complexity of mammalian tissues makes studying cell-type eQTLs highly challenging. We developed a novel...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ben-David, Eyal, Boocock, James, Guo, Longhua, Zdraljevic, Stefan, Bloom, Joshua S, Kruglyak, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062134/
https://ncbi.nlm.nih.gov/pubmed/33734084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65857
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