Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats

INTRODUCTION: Sodium glucose cotransporter-2 (SGLT2) inhibitors are widely used for diabetes treatment. Although SGLT2 inhibitors have been clinically observed to increase food intake, roles or even the presence of SGLT2 in the central nervous system (CNS) has not been established. We aimed to eluci...

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Detalhes bibliográficos
Publicado no:BMJ Open Diabetes Res Care
Main Authors: Takeda, Kenji, Ono, Hiraku, Ishikawa, Ko, Ohno, Tomohiro, Kumagai, Jin, Ochiai, Hidetoshi, Matumoto, Ai, Yokoh, Hidetaka, Maezawa, Yoshiro, Yokote, Koutaro
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061802/
https://ncbi.nlm.nih.gov/pubmed/33879516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-002104
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