Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats

INTRODUCTION: Sodium glucose cotransporter-2 (SGLT2) inhibitors are widely used for diabetes treatment. Although SGLT2 inhibitors have been clinically observed to increase food intake, roles or even the presence of SGLT2 in the central nervous system (CNS) has not been established. We aimed to eluci...

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Publicat a:BMJ Open Diabetes Res Care
Autors principals: Takeda, Kenji, Ono, Hiraku, Ishikawa, Ko, Ohno, Tomohiro, Kumagai, Jin, Ochiai, Hidetoshi, Matumoto, Ai, Yokoh, Hidetaka, Maezawa, Yoshiro, Yokote, Koutaro
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2021
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061802/
https://ncbi.nlm.nih.gov/pubmed/33879516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-002104
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