An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development

The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic series of Sox2 conditional mutations in mouse, delet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Open Biol
Egile Nagusiak: Mercurio, Sara, Alberti, Chiara, Serra, Linda, Meneghini, Simone, Berico, Pietro, Bertolini, Jessica, Becchetti, Andrea, Nicolis, Silvia K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061699/
https://ncbi.nlm.nih.gov/pubmed/33622105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200339
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak