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An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development
The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic series of Sox2 conditional mutations in mouse, delet...
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| Publicado no: | Open Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8061699/ https://ncbi.nlm.nih.gov/pubmed/33622105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200339 |
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