The Severe Acute Respiratory Syndrome (SARS) Coronavirus NTPase/Helicase Belongs to a Distinct Class of 5′ to 3′ Viral Helicases

The putative NTPase/helicase protein from severe acute respiratory syndrome coronavirus (SARS-CoV) is postulated to play a number of crucial roles in the viral life cycle, making it an attractive target for anti-SARS therapy. We have cloned, expressed, and purified this protein as an N-terminal hexa...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Tanner, Julian A., Watt, Rory M., Chai, Yu-Bo, Lu, Lin-Yu, Lin, Marie C., Peiris, J.S.Malik, Poon, Leo L.M., Kung, Hsiang-Fu, Huang, Jian-Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2003
Schlagworte:
Enzyme Catalysis and Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060950/
https://ncbi.nlm.nih.gov/pubmed/12917423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C300328200
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