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DNA methylation modifies urine biomarker levels in 1,6-hexamethylene diisocyanate exposed workers: A pilot study

DNA methylation may mediate inter-individual responses to chemical exposure and, thus, modify biomarker levels of exposure and effects. We analyzed inter-individual differences in inhalation and skin exposure to 1,6-hexamethylene diisocyanate (HDI) and urine biomarker 1,6-hexamethylene diamine (HDA)...

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Publicat a:Toxicol Lett
Autors principals: Nylander-French, Leena A., Wu, Michael C., French, John E., Boyer, Jayne C., Smeester, Lisa, Sanders, Alison P., Fry, Rebecca C.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060918/
https://ncbi.nlm.nih.gov/pubmed/25445006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2014.10.024
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