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Respiratory depression and analgesia by opioid drugs in freely behaving larval zebrafish

An opioid epidemic is spreading in North America with millions of opioid overdoses annually. Opioid drugs, like fentanyl, target the mu opioid receptor system and induce potentially lethal respiratory depression. The challenge in opioid research is to find a safe pain therapy with analgesic properti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zaig, Shenhab, da Silveira Scarpellini, Carolina, Montandon, Gaspard
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060028/
https://ncbi.nlm.nih.gov/pubmed/33720013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63407
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