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A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism

The interplay between nutrient-induced signaling and metabolism plays an important role in maintaining homeostasis and its malfunction has been implicated in many different human diseases such as obesity, type 2 diabetes, cancer, and neurological disorders. Therefore, unraveling the role of nutrient...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Comput Biol
Main Authors: Österberg, Linnea, Domenzain, Iván, Münch, Julia, Nielsen, Jens, Hohmann, Stefan, Cvijovic, Marija
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059808/
https://ncbi.nlm.nih.gov/pubmed/33836000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008891
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