The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

BACKGROUND: The gut microbiota–intestine–liver relationship is emerging as an important factor in multiple hepatic pathologies, but the hepatic sensors and effectors of microbial signals are not well defined. RESULTS: By comparing publicly available liver transcriptomics data from conventional vs. g...

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Bibliografiska uppgifter
I publikationen:Microbiome
Huvudupphovsmän: Barretto, Sharon Ann, Lasserre, Frederic, Huillet, Marine, Régnier, Marion, Polizzi, Arnaud, Lippi, Yannick, Fougerat, Anne, Person, Elodie, Bruel, Sandrine, Bétoulières, Colette, Naylies, Claire, Lukowicz, Céline, Smati, Sarra, Guzylack, Laurence, Olier, Maïwenn, Théodorou, Vassilia, Mselli-Lakhal, Laila, Zalko, Daniel, Wahli, Walter, Loiseau, Nicolas, Gamet-Payrastre, Laurence, Guillou, Hervé, Ellero-Simatos, Sandrine
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2021
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059225/
https://ncbi.nlm.nih.gov/pubmed/33879258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-021-01050-9
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