Establishment of functional epithelial organoids from human lacrimal glands

BACKGROUND: Tear deficiency due to lacrimal gland (LG) dysfunction is one of the major causes of dry eye disease (DED). Therefore, LG stem cell-based therapies have been extensively reported to regenerate injured lacrimal tissue; however, the number of stem cells in the LG tissue is low, and 2D long...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Jeong, Sang Yun, Choi, Woo Hee, Jeon, Seong Gyeong, Lee, Sookon, Park, Jong-Moon, Park, Mira, Lee, Hookeun, Lew, Helen, Yoo, Jongman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059179/
https://ncbi.nlm.nih.gov/pubmed/33883032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02133-y
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