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STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis (MS) is a debilitating neurological disease caused by autoimmune destruction of the myelin sheath. Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the pathogenesis of MS. We and others have previously demonstrated that IL-17 is critica...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhao, Junjie, Liao, Yun, Miller-Little, William, Xiao, Jianxing, Liu, Caini, Li, Xiaoxia, Li, Xiao, Kang, Zizhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059164/
https://ncbi.nlm.nih.gov/pubmed/33879167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02146-7
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