Externally triggered smart drug delivery system encapsulating idarubicin shows superior kinetics and enhances tumoral drug uptake and response

Rationale: Increasing the bioavailable drug level in a tumor is the key to enhance efficacy of chemotherapy. Thermosensitive smart drug delivery systems (SDDS) in combination with local hyperthermia facilitate high local drug levels, thus improving uptake in the tumor. However, inability to rapidly...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Lu, Tao, Haemmerich, Dieter, Liu, Hui, Seynhaeve, Ann L.B., van Rhoon, Gerard C., Houtsmuller, Adriaan B., ten Hagen, Timo L.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058728/
https://ncbi.nlm.nih.gov/pubmed/33897876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55163
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