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IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children
BACKGROUND: Interferon (IFN)- λ4, a type III IFN, production is controlled by a dinucleotide frameshift variant (rs368234815-dG/TT) within the first exon of the IFNL4 gene. Carriers of the IFNL4-dG allele but not the IFNL4-TT allele are able to produce the IFN-λ4 protein. Patients with hepatitis C v...
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| Publicado no: | Malar J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8058600/ https://ncbi.nlm.nih.gov/pubmed/33882912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03689-z |
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