Evidence of upregulation of the cholinergic anti-inflammatory pathway in late-life depression

BACKGROUND: Decreased cholinergic tone associated with increased proinflammatory cytokines has been observed in several human diseases associated with low-grade inflammation. We examined if this attenuated cholinergic anti-inflammatory pathway (CAP) mechanism contributes to increased neuroinflammati...

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Veröffentlicht in:J Affect Disord
Hauptverfasser: Pomara, Nunzio, Bruno, Davide, Plaska, Chelsea Reichert, Pillai, Anilkumar, Ramos-Cejudo, Jaime, Osorio, Ricardo, Imbimbo, Bruno P, Heslegrave, Amanda, Zetterberg, Henrik, Blennow, Kaj
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058311/
https://ncbi.nlm.nih.gov/pubmed/33756305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2021.03.012
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