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Therapeutic and prophylactic effects of macrophage-derived small extracellular vesicles in the attenuation of inflammatory pain

Small extracellular vesicles (sEVs) derived from antigen-presenting cells such as macrophages can induce therapeutically relevant immune responses. Anti-inflammatory miRNAs are elevated in sEVs secreted by RAW 264.7 mouse macrophages after lipopolysaccharide (LPS) stimulation. We observed uptake of...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Jean-Toussaint, Renée, Lin, Zhucheng, Tian, Yuzhen, Gupta, Richa, Pande, Richa, Luo, Xuan, Hu, Huijuan, Sacan, Ahmet, Ajit, Seena K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058272/
https://ncbi.nlm.nih.gov/pubmed/33607232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2021.02.005
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