A wake-like state in vitro induced by transmembrane TNF/soluble TNF receptor reverse signaling

Tumor necrosis factor alpha (TNF) has sleep regulatory and brain development roles. TNF promotes sleep in vivo and in vitro while TNF inhibition diminishes sleep. Transmembrane (tm) TNF and the tmTNF receptors (Rs), are cleaved by tumor necrosis factor alpha convertase to produce soluble (s) TNF and...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Dykstra-Aiello, Cheryl, Koh, Khia Min Sabrina, Nguyen, Joseph, Xue, Mengran, Roy, Sandip, Krueger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058269/
https://ncbi.nlm.nih.gov/pubmed/33571627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2021.01.036
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