Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model of Toxicant-Triggered Lupus

Workplace exposure to respirable crystalline silica dust (cSiO(2)) has been etiologically linked to the development of lupus and other human autoimmune diseases. Lupus triggering can be recapitulated in female NZBWF1 mice by four weekly intranasal instillations with 1 mg cSiO(2.) This elicits inflam...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Pestka, James J., Akbari, Peyman, Wierenga, Kathryn A., Bates, Melissa A., Gilley, Kristen. N., Wagner, James G., Lewandowski, Ryan P., Rajasinghe, Lichchavi D., Chauhan, Preeti S., Lock, Adam L., Li, Quan-Zhen, Harkema, Jack R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058219/
https://ncbi.nlm.nih.gov/pubmed/33897700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653464
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