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Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer

Higher epidermal growth factor receptor (EGFR) signaling can contribute to tumor metastasis and resistance to therapies in oral squamous cell carcinoma (OSCC). EGFR signaling can promote epithelial-mesenchymal transition (EMT) in OSCC. EMT is a process by which epithelial cells acquire invasive prop...

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Pubblicato in:Oncotarget
Autori principali: Gudi, Radhika R., Janakiraman, Harinarayanan, Howe, Philip H., Palanisamy, Viswanathan, Vasu, Chenthamarakshan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057274/
https://ncbi.nlm.nih.gov/pubmed/33889303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27932
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