Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer’s disease

BACKGROUND: Sepsis, a leading cause for intensive care unit admissions, causes both an acute encephalopathy and chronic brain dysfunction in survivors. A history of sepsis is also a risk factor for future development of dementia symptoms. Similar neuropathologic changes are associated with the cogni...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Basak, Jacob M., Ferreiro, Aura, Cohen, Lucy S., Sheehan, Patrick W., Nadarajah, Collin J., Kanan, Michael F., Sukhum, Kimberley V., Dantas, Gautam, Musiek, Erik S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057119/
https://ncbi.nlm.nih.gov/pubmed/33556539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2021.105292
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