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Increased risk of skin cancer in Japanese heterozygotes of xeroderma pigmentosum group A

This study was designed to learn if asymptomatic heterozygotes with mutations in a DNA repair gene are at an increased risk for cancer. To examine this, we focused on carriers of an XPA founder mutation because the frequency of xeroderma pigmentosum (XP) patients is much greater among Japanese than...

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Podrobná bibliografie
Vydáno v:J Hum Genet
Hlavní autoři: Hirai, Yuko, Noda, Asao, Kodama, Yoshiaki, Cordova, Kismet A., Cullings, Harry M., Yonehara, Shuji, Fujihara, Megumu, Moriwaki, Shin-ichi, Nishigori, Chikako, Mabuchi, Kiyohiko, Kraemer, Kenneth H., Nakamura, Nori
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057111/
https://ncbi.nlm.nih.gov/pubmed/30089811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-018-0495-y
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