Advances in epigenetic therapeutics with focus on solid tumors

Epigenetic (“above genetics”) modifications can alter the gene expression without altering the DNA sequence. Aberrant epigenetic regulations in cancer include DNA methylation, histone methylation, histone acetylation, non-coding RNA, and mRNA methylation. Epigenetic-targeted agents have demonstrated...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Jin, Ning, George, Tiffany L., Otterson, Gregory A., Verschraegen, Claire, Wen, Haitao, Carbone, David, Herman, James, Bertino, Erin M., He, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056722/
https://ncbi.nlm.nih.gov/pubmed/33879235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01069-7
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