Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer

The renin-angiotensin system (RAS) is up-regulated in patients with colorectal cancer (CRC) and is reported to be associated with poor prognosis and chemo-resistance. Here we explored the therapeutic potential of targeting RAS in CRC using Losartan, an angiotensin receptor blocker. An integrative-sy...

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Vydáno v:EXCLI J
Hlavní autoři: Hashemzehi, Milad, Rahmani, Farzad, Khoshakhlagh, Mahdieh, Avan, Amir, Asgharzadeh, Fereshteh, Barneh, Farnaz, Moradi-Marjaneh, Reyhaneh, Soleimani, Atena, Fiuji, Hamid, Ferns, Gordon A., Ryzhikov, Mikhail, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi
Médium: Artigo
Jazyk:Inglês
Vydáno: Leibniz Research Centre for Working Environment and Human Factors 2021
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056058/
https://ncbi.nlm.nih.gov/pubmed/33883980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-3083
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