Exosome-Mediated Delivery of the Neuroprotective Peptide PACAP38 Promotes Retinal Ganglion Cell Survival and Axon Regeneration in Rats With Traumatic Optic Neuropathy

Traumatic optic neuropathy (TON) refers to optic nerve damage caused by trauma, leading to partial or complete loss of vision. The primary treatment options, such as hormonal therapy and surgery, have limited efficacy. Pituitary adenylate cyclase-activating polypeptide 38 (PACAP38), a functional end...

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Publicat a:Front Cell Dev Biol
Autors principals: Wang, Tian, Li, Yiming, Guo, Miao, Dong, Xue, Liao, Mengyu, Du, Mei, Wang, Xiaohong, Yin, Haifang, Yan, Hua
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055942/
https://ncbi.nlm.nih.gov/pubmed/33889576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.659783
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