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The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis

The human orthologue of the tumor suppressor protein FBW7 is encoded by the Drosophila archipelago (ago) gene. Ago is an F-box protein that gives substrate specificity to its SCF ubiquitin ligase complex. It has a central role in multiple biological processes in a tissue-specific manner such as cell...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Vedelek, Viktor, Kovács, Attila L., Juhász, Gábor, Alzyoud, Elham, Sinka, Rita
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055871/
https://ncbi.nlm.nih.gov/pubmed/33875704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87656-3
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