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Within-subject, double-blinded, randomized, and placebo-controlled evaluation of the combined effects of the cannabinoid dronabinol and the opioid hydromorphone in a human laboratory pain model

This Phase II study evaluated analgesia, abuse liability, and cognitive performance of hydromorphone and oral delta-9-tetrahydrocannabinol (THC; dronabinol) using a within-subject, double-blind, randomized, placebo-controlled, human laboratory trial. Healthy adults (N = 29) with no history of drug u...

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Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Dunn, Kelly E., Bergeria, Cecilia L., Huhn, Andrew S., Speed, Traci J., Mun, Chung Jung, Vandrey, Ryan, Campbell, Claudia M.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055479/
https://ncbi.nlm.nih.gov/pubmed/33879842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-021-01007-4
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