Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease: A Mendelian Randomization Study

OBJECTIVE: We employed Mendelian randomization to explore the effects of genetic predisposition to type 2 diabetes (T2D), hyperglycemia, insulin resistance, and pancreatic β-cell dysfunction on risk of stroke subtypes and related cerebrovascular phenotypes. METHODS: We selected instruments for genet...

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Bibliographic Details
Published in:Neurology
Main Authors: Georgakis, Marios K., Harshfield, Eric L., Malik, Rainer, Franceschini, Nora, Langenberg, Claudia, Wareham, Nicholas J., Markus, Hugh S., Dichgans, Martin
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055310/
https://ncbi.nlm.nih.gov/pubmed/33495378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011555
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