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Inferring molecular mechanisms of dexamethasone therapy in severe COVID-19 from existing transcriptomic data

Dexamethasone, a synthetic glucocorticoid, has previously shown mortality benefit in severe coronavirus disease 2019 (COVID-19) in a randomized controlled trial. As the illness is considered to reflect a hyperinflammatory state, this therapeutic effectiveness is presumably ascribed to broad anti-inf...

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Detalhes bibliográficos
Publicado no:Gene
Autor principal: Sharma, Abhay
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054526/
https://ncbi.nlm.nih.gov/pubmed/33887367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2021.145665
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