PTEN loss correlates with T cell exclusion across human cancers

BACKGROUND: Recent evidences had shown that loss in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was associated with immunotherapy resistance, which may be attributed to the non-T-cell-inflamed tumor microenvironment. The impact of PTEN loss on tumor microenvironment, especially re...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Lin, Ziying, Huang, Lixia, Li, Shao Li, Gu, Jincui, Cui, Xiaoxian, Zhou, Yanbin
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054401/
https://ncbi.nlm.nih.gov/pubmed/33874915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08114-x
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