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Thermodynamics of Macromolecular Association in Heterogeneous Crowding Environments: Theoretical and Simulation Studies with a Simplified Model

The cytoplasm of a cell is crowded with many different kinds of macromolecules. The macromolecular crowding affects the thermodynamics and kinetics of biological reactions in a living cell, such as protein folding, association, and diffusion. Theoretical and simulation studies using simplified model...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Ando, Tadashi, Yu, Isseki, Feig, Michael, Sugita, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054318/
https://ncbi.nlm.nih.gov/pubmed/27797534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b06243
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