The role of neutrophil extracellular traps and TLR signaling in skeletal muscle ischemia reperfusion injury

Ischemia reperfusion (IR) injury results in devastating skeletal muscle fibrosis. Here, we recapitulate this injury with a mouse model of hindlimb IR injury which leads to skeletal muscle fibrosis. Injury resulted in extensive immune infiltration with robust neutrophil extracellular trap (NET) forma...

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Publicat a:FASEB J
Autors principals: Edwards, Nicole J., Hwang, Charles, Marini, Simone, Pagani, Chase A., Spreadborough, Philip J., Rowe, Cassie J., Yu, Pauline, Mei, Annie, Visser, Noelle, Li, Shuli, Hespe, Geoffrey E., Huber, Amanda K., Strong, Amy L., Shelef, Miriam A., Knight, Jason S., Davis, Thomas A., Levi, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054227/
https://ncbi.nlm.nih.gov/pubmed/33089917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000994RR
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