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Cholinergic suppression of hippocampal sharp-wave ripples impairs working memory
Learning and memory are assumed to be supported by mechanisms that involve cholinergic transmission and hippocampal theta. Using G protein–coupled receptor-activation–based acetylcholine sensor (GRAB(ACh)3.0) with a fiber-photometric fluorescence readout in mice, we found that cholinergic signaling...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054002/ https://ncbi.nlm.nih.gov/pubmed/33833054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016432118 |
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