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Armored CAR T-Cells: The Next Chapter in T-Cell Cancer Immunotherapy

Chimeric antigen receptor (CAR) T-cell therapy engineers T-cells to express a synthetic receptor which redirects effector function to the tumor, to improve efficacy and reduce toxicities associated with conventional treatments, such as radiotherapy and chemotherapy. This approach has proved effectiv...

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Detalles Bibliográficos
Publicado en:Biologics
Main Authors: Hawkins, Elizabeth R, D’Souza, Reena R, Klampatsa, Astero
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053711/
https://ncbi.nlm.nih.gov/pubmed/33883875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S291768
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