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Age-dependency of terminal ileum tissue resident memory T cell responsiveness profiles to S. Typhi following oral Ty21a immunization in humans

BACKGROUND: The impact of aging on the immune system is unequivocal and results in an altered immune status termed immunosenescence. In humans, the mechanisms of immunosenescence have been examined almost exclusively in blood. However, most immune cells are present in tissue compartments and exhibit...

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Bibliographische Detailangaben
Veröffentlicht in:Immun Ageing
Hauptverfasser: Booth, Jayaum S., Goldberg, Eric, Patil, Seema A., Barnes, Robin S., Greenwald, Bruce D., Sztein, Marcelo B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053564/
https://ncbi.nlm.nih.gov/pubmed/33874975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-021-00227-y
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