SLAMs Negatively Regulate IL-21 Production in Tfh-Like Cells from Allergic Rhinitis Patients

BACKGROUND: Allergic rhinitis (AR) is characterized by type I hypersensitivity that is mediated by IgE-induced humoral responses. Follicular helper T cells (Tfh) comprise the key helper T cell (Th) subset that promotes antibody production. Signaling lymphocytic activation molecules (SLAMs) participa...

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Pubblicato in:J Asthma Allergy
Autori principali: Yang, Jun, Geng, Lina, Ma, Yongmin, Tang, Xinyi, Peng, Huiyong, Tian, Jie, Xu, Huaxi, Wang, Shengjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053523/
https://ncbi.nlm.nih.gov/pubmed/33880041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S291879
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